This study investigates the toxic effects of ZnO-NPs in human lung cells. A severe to slight damage was observed in liver tissue in all groups and tissue destruction was seen in kidney only in acute dose treated groups but no specific pathological effect in testis was observed (Fig. RESEARCH ARTICLE Zinc oxide and silver nanoparticles toxicity in the baker’s yeast, Saccharomyces cerevisiae Imelda Galva´ n Ma´ rquez1, Mergan Ghiyasvand1, Andrey Massarsky2¤, Mohan Babu3, Bahram Samanfar1,4, Katayoun Omidi1, Thomas W. Moon2, Myron L. Smith1*, Ashkan Golshani1* 1 Department of Biology and Ottawa Institute of Systems Biology, Carleton University, … Faddah LM, Abdel Baky NA, Al-Rasheed NM, Al-Rasheed NM, Fatani AJ, Atteya M. BMC Complement Altern Med. Happy Agarwal, Soumya Menon, Venkat Kumar S, Rajeshkumar S. Chem Biol Interact. Keywords: Antimicrobial activity; Cytotoxicity; Nanoparticles; Nanotechnology; Synthesis; Zinc oxide. Xia T, Kovochich M, Liong M, et al. Accute Toxicity Satureja ZnO Nanoparticles Bioassay Test LC 50 96h Abstract Nanoparticles are commonly synthesized chemically and because of their risk for living was carried out to evaluate the acute toxicity of zinc oxide nanoparticles synthesized from Satureja hortensis on rainbow trout (Oncorhynchus mykiss) by static bioassay test. ZnO induced toxicity in both cells, leading to the generation of reactive oxygen species (ROS), oxidant injury, excitation of inflammation, and cell death. Comparison of the mechanism of toxicity of zinc oxide and cerium oxide nanoparticles based on dissolution and oxidative stress properties. The increasing focus on nano zinc oxide resulted in the invention and development of methods of nanoparticles synthesis. ; nano-zinc oxide; oxidative stress. Zinc oxide nanoparticles (ZnO NPs) are being utilized in an increasing number of fields and commercial applications. eCollection 2020. Zinc oxide nanoparticles induced cyto- and genotoxicity in kidney epithelial cells. 2020 Nov 11;12(11):3457. doi: 10.3390/nu12113457. Epub 2015 May 18.  |  COVID-19 is an emerging, rapidly evolving situation. A comprehensive toxicity study of zinc oxide nanoparticles versus their bulk in Wistar rats: Toxicity study of zinc oxide nanoparticles. This helps to place the in vivo behavior of zinc oxide nanoparticles in the proper context. There were significant decreases in lymphocytes and platelet counts and significant increases in white blood cells count, hemoglobin and hematocrit in acute dose compared to control group and no difference in red blood cells count in all groups. 2016 Aug;161:441-9. doi: 10.1016/j.jphotobiol.2016.06.007. Corrigendum to "Zinc oxide nanoparticles: synthesis, antiseptic activity and toxicity mechanism" Adv Colloid Interface Sci 249 (2017) 37-52. Microb Pathog. Wang LJ, Wang L, Ding WJ, Zhang F: Acute toxicity of ferric oxide and zinc oxide nanoparticles in rats. Zinc oxide nanocomposites show also selective toxicity toward normal and cancerous cells, which is explained by reactive oxygen formation (ROS). COVID-19 is an emerging, rapidly evolving situation. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. The purpose of this study was to characterize the zinc oxide nanoparticles (ZnO-NPs) and their bulk counterpart in suspensions and to access the impact of their acute oral toxicity at doses of 300 and 2000 mg/kg in healthy female Wistar rats. 2014;6(24):15333–15342. Biosynthesis of zinc oxide nanoparticles using.  |  The purpose of this study was to characterize the zinc oxide nanoparticles (ZnO-NPs) and their bulk counterpart in suspensions and to access the impact of their acute oral toxicity at doses of 300 and 2000 mg/kg in healthy female Wistar rats.  |  ZnO nanopowders are available as powders and dispersions. 2016 Dec;35(12):1286-1304. doi: 10.1177/0960327116629530. 2018 Dec;125:252-261. doi: 10.1016/j.micpath.2018.09.030. 2020 Dec 10;5(50):32203-32215. doi: 10.1021/acsomega.0c03634. NIH This paper reviews the methods of synthesizing zinc oxide nanocomposites as well as their characteristics, antimicrobial activity and cytotoxicity against normal and tumor cells. eCollection 2020. Effects of zinc oxide nanoparticles and/or zinc chloride on biochemical parameters and mineral levels in rat liver and kidney. Hidden toxicity of zinc oxide nanoparticles. The nanoparticles (NPs) have been increasingly manufactured in industry because of the well-known characteristics such as high reactivity, electromagnetic properties and high antibacterial property [].Zinc oxide nanoparticle (nZnO), one of the most popular manufactured metal oxide nanomaterials, has unique properties (i.e., surface area and reactive sites) due to the extremely small … In the present study 36 male Wistar rats with approximate age of two months and weighing 300±30 g were selected. Zinc oxide nanoparticles (ZnO-NPs) have been reported as an antimicrobial agent against both pathogenic and spoilage microorganisms ... L. C., Bakhori, S. K. M., Mohamad, D., Review on zinc oxide nanoparticles: Antibacterial activity and toxicity mechanism. Results: ISRN Toxicol 2013; 2013: 316075. Epub 2018 Mar 15. Khan MF, Husain FM, Zia Q, Ahmad E, Jamal A, Alaidarous M, Banawas S, Alam MM, Alshehri BA, Jameel M, Alam P, Ahamed MI, Ansari AH, Ahmad I. ACS Omega. Amara S, Slama IB, Mrad I, Rihane N, Khemissi W, El Mir L, Rhouma KB, Abdelmelek H, Sakly M. Hum Exp Toxicol. Zinc oxide NPs can be synthesized by a number of physical, chemical and biological methods. DOI: 10.1007/s40820-015-0040-x Corpus ID: 3669662. Review on Zinc Oxide Nanoparticles: Antibacterial Activity and Toxicity Mechanism @article{Sirelkhatim2015ReviewOZ, title={Review on Zinc Oxide Nanoparticles: Antibacterial Activity and Toxicity Mechanism}, author={Amna Sirelkhatim and S. Mahmud and A. Seeni and Noor Haida Mohamad Kaus and Ling Chuo Ann and S. K. M. Bakhori and … ZnO nanomaterials can be used in industry as nano-optical and nano-electrical devices, in food packaging and in medicine as antimicrobial and antitumor agents. In the present study, it was found that ZnO‐engineered nanoparticle (ZnO‐EN) toxicity to the marine diatom Thalassiosira pseudonana could be solely explained by … Nanoscale. Azizi S, Mohamad R, Bahadoran A, Bayat S, Rahim RA, Ariff A, Saad WZ. Recently, various approaches including physical, chemical and biological ("green chemistry") have been used to prepare ZnO nanocomposites with different morphologies. Franklinet al. Toxicity of zinc oxide nanoparticles on adult male Wistar rats. With the wide application of ZnO-NPs, concern has been raised about its unintentional health and environmental impacts. Int J Nanomedicine. Clipboard, Search History, and several other advanced features are temporarily unavailable. HHS 2015 Oct;84:154-60. doi: 10.1016/j.fct.2015.08.019. There is a single study of repeated skin exposure in rats (ten per cent of body area treated for five days a week, over four weeks). Zinc oxide nanoparticles (ZnO NPs) are being utilized in an increasing number of fields and commercial applications. 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